Kisan Thapa
Projects
Project CausalPath Webserver

CausalPath Webserver

CausalPath works on a set of molecular profiles and predicts the causal mechanisms that acts on the data. It integrates prior knowledge from biological pathway databases, and uses them to explain new observations. While the main focus is phosphoproteomics, CausalPath can also work on global proteomic, transcriptomic, acetylomic and methylomic profiles, and combinations of them.

GitHub Project

CausalPath Webserver

Project: Transcription Factor Activity Prediction

Transcription Factor Activity Prediction

Transcription factors (TFs) are proteins that bind to specific DNA sequences and regulate the transcription of genes. TF activity prediction is a challenging problem in computational biology. This project aims to predict the activity of TFs from gene expression data using rank-based methods. The project is implemented as a webserver that takes gene expression data as input and predicts the activity of TFs.

GitHub Project